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Richard W Light Selected Research

Empyema

3/2019A novel diagnostic method for distinguishing parapneumonic effusion and empyema from other diseases by using the pleural lactate dehydrogenase to adenosine deaminase ratio and carcinoembryonic antigen levels.
1/2019Phase 1 trial of intrapleural LTI-01; single chain urokinase in complicated parapneumonic effusions or empyema.
7/2013Black pleural effusion.
10/2009Single-chain urokinase in empyema induced by Pasturella multocida.
1/2008New trends in the diagnosis and treatment in parapneumonic effusion and empyema.
11/2006Intrapleural heparin or heparin combined with human recombinant DNase is not effective in the treatment of empyema in a rabbit model.
6/2006Tissue plasminogen activator combined with human recombinant deoxyribonuclease is effective therapy for empyema in a rabbit model.

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Richard W Light Research Topics

Disease

39Pleural Effusion (Pleural Effusions)
11/2018 - 01/2002
10Malignant Pleural Effusion
01/2018 - 12/2003
10Fibrosis (Cirrhosis)
01/2016 - 01/2002
10Inflammation (Inflammations)
10/2012 - 09/2002
9Pneumothorax
12/2018 - 02/2003
7Empyema
03/2019 - 06/2006
7Heart Failure
04/2013 - 07/2003
5Neoplasms (Cancer)
01/2018 - 07/2004
5Pain (Aches)
02/2011 - 08/2002
4Melanoma (Melanoma, Malignant)
04/2019 - 07/2013
4Pneumonia (Pneumonitis)
03/2018 - 01/2007
4Eosinophilia
01/2008 - 07/2003
3Pleural Diseases
11/2020 - 10/2007
3Pulmonary Embolism
12/2010 - 07/2003
3Critical Illness (Critically Ill)
01/2008 - 01/2007
3Fever (Fevers)
06/2004 - 07/2002
2Malignant Mesothelioma
04/2019 - 03/2019
2Lymphoma (Lymphomas)
03/2019 - 05/2015
2Neoplasm Metastasis (Metastasis)
03/2019 - 11/2018
2Hemorrhage
01/2019 - 07/2013
2Pleural Tuberculosis
01/2018 - 12/2004
2Pleurisy (Pleuritis)
01/2015 - 04/2010
2Carcinoma (Carcinomatosis)
06/2010 - 01/2008
2Necrosis
01/2008 - 11/2005
2Delirium
09/2007 - 01/2007
2Chronic Obstructive Pulmonary Disease (COPD)
11/2005 - 02/2003
2Respiratory Insufficiency (Respiratory Failure)
12/2003 - 09/2002
1Adenocarcinoma of Lung
04/2019
1Lung Neoplasms (Lung Cancer)
03/2019
1Adenocarcinoma
03/2019
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2019
1Small Cell Carcinoma
03/2019
1Aspergillosis
07/2013
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2013
1Fistula
07/2013
1Hemolysis
07/2013
1Pancreatic Pseudocyst
07/2013
1Rupture
07/2013
1Ischemia
11/2011
1Thrombosis (Thrombus)
02/2011
1Barotrauma
02/2011
1Chylothorax
12/2010
1Philadelphia Chromosome
07/2010
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
07/2010
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
07/2010

Drug/Important Bio-Agent (IBA)

7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2012 - 01/2002
7TalcFDA Link
07/2012 - 01/2002
5Brain Natriuretic Peptide (Natrecor)FDA Link
04/2013 - 06/2006
4Adenosine DeaminaseIBA
03/2019 - 12/2004
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2008 - 11/2005
4Pharmaceutical PreparationsIBA
09/2007 - 07/2003
4InterleukinsIBA
10/2005 - 08/2002
3L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
03/2019 - 05/2015
3pro-brain natriuretic peptide (1-76)IBA
04/2013 - 01/2008
3Proteins (Proteins, Gene)FDA Link
03/2013 - 02/2007
3Silver NitrateIBA
07/2007 - 08/2005
3Interleukin-5 (Interleukin 5)IBA
10/2005 - 08/2002
2Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
01/2019 - 10/2009
2Melanins (Melanin)IBA
11/2018 - 07/2013
2Anti-Bacterial Agents (Antibiotics)IBA
03/2018 - 01/2008
2Biomarkers (Surrogate Marker)IBA
01/2018 - 11/2011
2AcidsIBA
09/2016 - 07/2013
2BilirubinIBA
09/2016 - 07/2013
2CollagenIBA
01/2016 - 10/2012
2CytokinesIBA
01/2012 - 10/2007
2Glucose (Dextrose)FDA LinkGeneric
01/2012 - 07/2003
2fibrin fragment D (D-dimer)IBA
12/2010 - 10/2009
2SteroidsIBA
01/2010 - 01/2008
2AngiopoietinsIBA
03/2009 - 05/2006
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2008 - 01/2002
2NF-kappa B (NF-kB)IBA
10/2007 - 02/2006
2AgarIBA
11/2006 - 06/2006
2Deoxyribonucleases (DNase)FDA Link
11/2006 - 06/2006
2Heparin (Liquaemin)FDA LinkGeneric
11/2006 - 01/2005
2Oxygen (Dioxygen)IBA
11/2005 - 02/2003
2Doxycycline (Periostat)FDA LinkGeneric
11/2005 - 01/2002
2Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
06/2005 - 07/2003
2AsbestosIBA
07/2004 - 07/2003
1MART-1 AntigenIBA
04/2019
1AntigensIBA
04/2019
1Carcinoembryonic AntigenIBA
03/2019
1fibrinolytic agent LTI-01IBA
01/2019
1Fibrin Tissue Adhesive (Fibrin Sealant)IBA
01/2016
1Charcoal (Charbon)IBA
07/2013
1AmylasesFDA Link
07/2013
1Atrial Natriuretic Factor (ANF)IBA
04/2013
1AdrenomedullinIBA
04/2013
1Serum AlbuminIBA
05/2012
1ischemia-modified albuminIBA
11/2011
1Triglycerides (Triacylglycerol)IBA
12/2010
1Imatinib Mesylate (Gleevec)FDA Link
07/2010
1Dasatinib (BMS 354825)FDA Link
07/2010

Therapy/Procedure

18Pleurodesis
01/2016 - 01/2002
7Coronary Artery Bypass (Coronary Artery Bypass Surgery)
06/2010 - 07/2002
6Therapeutics
01/2008 - 02/2003
5Chest Tubes (Chest Tube)
12/2018 - 07/2002
4Catheters
11/2020 - 01/2005
2Artificial Respiration (Mechanical Ventilation)
02/2011 - 01/2008
1Thrombolytic Therapy
01/2019
1Treatment Delay
03/2018